If you could have any superpower, what would you choose? Likely not the power to harness your used tissues into crime-fighting snot golems? Thirteen-year-old Jess Flem is riddled with every allergy, known and unknown. She's used to leaving a trail of soggy, used tissues wherever she goes, but not at all prepared for the mysterious powers that show around her thirteenth birthday. And just in the nick of time too, as it turns out there are forces both good and evil who have had their eyes on her and three other "special" kids since their birth, knowing this day might someday come. Exposed to a mysterious element in the maternity ward of a small-town hospital, these four children develop not-so-super powers at puberty, each with their own specific limitations and all more than slightly goofy. As each discovers his or her power and struggles to master it, each is in turn drawn into an epic (or epically silly?) battle only they can fight. Good Dr Fassbinder, expert on the mysterious element, keeps tabs on the youngsters, while working for a secret government department. His evil ex-assistant, Nurse Nussbaum, thought to have perished in an explosion, is in fact powerfully alive, invisible, and bent on controlling our heroes to further her schemes of world domination.