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You bet your life : from blood transfusions to mass vaccination, the long and risky history of medical innovations / by Offit, Paul A.,author.;
Includes bibliographical references and index."Four months into the coronavirus pandemic, as the death count surged, the FDA made a risky decision: it approved an anti-malarial drug as a treatment for coronavirus, despite limited data on its efficacy or side effects. A month later, the FDA withdrew its recommendation, but by then, the damage had been done. The drug was ineffective and sometimes even lethal. The mistake was hardly a one-off. As virologist Paul. A. Offit shows in You Bet Your Life, from antibiotics and vaccines to x-rays and genetic engineering, risk, and our understanding of it, have shaped the course of modern medicine, paving the way for its greatest triumphs and tragedies. By telling the stories of the events--and of the frequent hypocrisy and cravenness of the characters at their center--Offit shows how risk, and failure, have driven innovation, and importantly, how by examining our mistakes we can make better medical predictions and decisions going forward. From the outlandish origins of blood transfusions, which began with humans receiving blood for barnyard animals, to the the disastrous debut of the first polio vaccine, and the backstabbing and infighting that surrounded early gene therapies, he captures the drama that surrounds medical research, the way ego and laziness can collide with science, and ultimately how those factors should inform what we choose to do and have done to us in the clinic. The history is fascinating in its own right, but the worldwide rush to create a coronavirus vaccine only makes learning from the lessons of history essential. Weighing the uncertainties of a treatment against its potential benefits is one of medicine's greatest ethical dilemmas, and Offit examines it from every angle. He explores not just how patients and their families respond to risk but how everyone from physicians and researchers to universities and regulators do, too, and how that ultimately determines what treatments are put forward. Not everyone has the same goal. And too often the patient's health is secondary. But as Offit shows, we can all minimize risk and failure by learning how to recognize conflicts of interest, to draw inferences from animal models, and to evaluate risk, even when we have limited data. Along the way, Offit asks who should decide what risks are acceptable, and who should pay when the results are fatal. In the end, however, Offit argues that we are gambling whatever we do--and that we need to take that seriously, whether we pursue a treatment or decide to do nothing at all. The answers aren't simple, and the outcomes are life or death. Examining these questions with the compassion of a pediatrician and the rigor of a scientist, Offit reminds us that we all have a role to play in ensuring that medicine upholds its very first principle: to do no harm"--
Subjects: Medical ethics.; Risk assessment.; Pharmacology, Experimental.; Drugs;
Available copies: 1 / Total copies: 1
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Robert Ludlum's the Janson option / by Garrison, Paul,1952-; Ludlum, Robert,1927-2001.;
Ex-covert-ops soldier Paul Janson and his sharpshooting partner, Jessica Kincaid, set out to rescue the wife of an oil executive who has been kidnapped by Somali pirates.
Subjects: Spy stories.; Suspense fiction.; Intelligence officers; Kidnapping victims; Kidnapping; Janson, Paul (Fictitious character);
Available copies: 0 / Total copies: 2
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Fantasy art in watercolour : painting fairies, dragons, unicorns & angels / by Davies, Paul Bryn.; Balchin, Rebecca.; Hamer, Elaine.; Crispe, Steve.;
LSC
Subjects: Watercolor painting; Fantasy in art.;
© 2010., Search Press,
Available copies: 1 / Total copies: 1
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The Mistletoe Inn / by Evans, Richard Paul.;
"The second holiday love story in New York Times bestselling author Richard Paul Evans's Mistletoe Collection. At thirty-two Kimberly Rossetti, a finance officer at a Lexus car dealership, has had her heart broken more times than she wants to remember. With two failed engagements, a divorce and again alone with no prospects, she hardly seems the type to dream of being a published romance author. Dreading another holiday alone, she signs up for The Mistletoe Retreat, a nine-day writing retreat in Savannah, Georgia. Deep inside Kimberly knows she's at a junction in her life and it's time to either fulfill her dream or let it go. The other reason she decides to attend the conference is because famed romance writer, H.T. Cowell, once the best selling romance writer in America, and the author whose books instilled in her the desire to be a writer, will be speaking in public for the first time in more than a decade. In one of her breakout sessions Kimberly meets another aspiring writer, and one of the few men at the conference, Zeke, an intelligent man with a wry wit who seems as interested in Kimberly as he is in the retreat. As Kimberly begins to open up to him about her stories and dreams, she inadvertently reveals her own troubled past. As Zeke helps her to discover why her books fail to live up to their potential she begins to wonder if he's really talking more about her life than her literature. But as she grows closer to him, she realizes that Zeke has his own darkness, a past he's unwilling to talk about. The theme of The Mistletoe Inn is that like literature, relationships must be lived with passion and vulnerability to succeed"--Provided by publisher.
Subjects: Christmas stories.; Love stories.;
Available copies: 1 / Total copies: 1
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Estate planning for the blended family / by Hood, L. Paul,1960-; Bouchard, Emily.;
LSC
Subjects: Estate planning.; Stepfamilies.; Wills.;
© 2012., Self-Counsel Press,
Available copies: 1 / Total copies: 1
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Inside in : X-rays of nature's hidden world / by Schutten, Jan Paul,1970-; Riet, Arie van 't,1947-; Watkinson, Laura.;
LSC
Subjects: Animals; Animals; Radiography;
Available copies: 1 / Total copies: 1
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After the fire : Sainte-Marie among the Hurons since 1649 / by Delaney, Paul J., 1944-; Nicholls, Andrew D.,1965-; Golas, Irene; East Georgian Bay Historical Foundation;
Subjects: Martyrs' Shrine (Midland, Ont.); Huron Indians; Jesuits in Canada; Indians of North America;
© c1989., East Georgian Bay Historical Foundation,
Available copies: 1 / Total copies: 1
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Vehicle 19. by Walker, Paul;
Director, Makunda Michael Dewil.Paul Walker.Recently paroled Michael Woods just wants to get his life in order. But when he discovers a gun, a cell phone, and an unconscious woman in the trunk of a rental car, he fears he's in for the ride of his life. Michael has some serious decisions to make: keep his head down and hope to escape with his life, or risk it all to do the right thing.MPAA rating: R.DVD.
Subjects: Suspense.; Suspense / Thriller.;
© 2013., Arc Entertainment, Llc,
Available copies: 1 / Total copies: 1
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Sixty-one : life lessons from Papa, on and off the court / by Paul, Chris,1985-author.; Wilbon, Michael,author.;
"By the NBA superstar: A powerful and unexpected memoir of family, faith, tragedy, and life's most important lessons. The day after future NBA superstar Chris Paul signed his letter of intent to play college basketball for Wake Forest, he received a world-shattering phone call. His grandfather, Nathaniel "Papa" Jones, a pillar of the Winston-Salem community where he owned and operated the first Black-owned service station in North Carolina, was mugged and ultimately died from a heart attack resulting from the assault. His funeral filled the largest church in the county, which held over one thousand people. He was sixty-one years old. The day after burying his grandfather, Chris was coping the best way he knew how: by playing basketball for his high school team. After pouring in shot after shot, his last attempt was an airball purposely flung out of bounds from the foul line before Chris exited the game. The next day, local news headlines declared that he fell six points shy of the statewide single game high school scoring record. But he accomplished exactly what he set out to do: scoring sixty-one points, one for each year of life lived by his grandfather. In Sixty-One, Chris opens up about life beyond basketball and the role his grandfather played in molding him into the man and father he is today. He'll speak about the foundation of faith and family he built his life upon, what it means to be a positive light within your community and beyond, and the importance of setting the proper example for future generations. Most importantly, Chris will talk about his home, Winston-Salem, and the close-knit family and village that raised him to become one of the most respected leaders in all of sports"--
Subjects: Biographies.; Autobiographies.; Paul, Chris, 1985-; Paul, Chris, 1985-; Community life; Grandparent and child.;
Available copies: 1 / Total copies: 1
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Leonard and Hungry Paul : a novel / by Hession, Rónán,author.;
In this startling debut, Ronan Hession tells the story of two friends trying to find their place in the world. It is about the uncelebrated people of this world, the gentle, the meek. And it asks a surprisingly enthralling question: Can kind people change the world? A Dewey Diva Pick.
Subjects: Humorous fiction.; Male friendship;
Available copies: 1 / Total copies: 1
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