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You bet your life : from blood transfusions to mass vaccination, the long and risky history of medical innovations / by Offit, Paul A.,author.;
Includes bibliographical references and index."Four months into the coronavirus pandemic, as the death count surged, the FDA made a risky decision: it approved an anti-malarial drug as a treatment for coronavirus, despite limited data on its efficacy or side effects. A month later, the FDA withdrew its recommendation, but by then, the damage had been done. The drug was ineffective and sometimes even lethal. The mistake was hardly a one-off. As virologist Paul. A. Offit shows in You Bet Your Life, from antibiotics and vaccines to x-rays and genetic engineering, risk, and our understanding of it, have shaped the course of modern medicine, paving the way for its greatest triumphs and tragedies. By telling the stories of the events--and of the frequent hypocrisy and cravenness of the characters at their center--Offit shows how risk, and failure, have driven innovation, and importantly, how by examining our mistakes we can make better medical predictions and decisions going forward. From the outlandish origins of blood transfusions, which began with humans receiving blood for barnyard animals, to the the disastrous debut of the first polio vaccine, and the backstabbing and infighting that surrounded early gene therapies, he captures the drama that surrounds medical research, the way ego and laziness can collide with science, and ultimately how those factors should inform what we choose to do and have done to us in the clinic. The history is fascinating in its own right, but the worldwide rush to create a coronavirus vaccine only makes learning from the lessons of history essential. Weighing the uncertainties of a treatment against its potential benefits is one of medicine's greatest ethical dilemmas, and Offit examines it from every angle. He explores not just how patients and their families respond to risk but how everyone from physicians and researchers to universities and regulators do, too, and how that ultimately determines what treatments are put forward. Not everyone has the same goal. And too often the patient's health is secondary. But as Offit shows, we can all minimize risk and failure by learning how to recognize conflicts of interest, to draw inferences from animal models, and to evaluate risk, even when we have limited data. Along the way, Offit asks who should decide what risks are acceptable, and who should pay when the results are fatal. In the end, however, Offit argues that we are gambling whatever we do--and that we need to take that seriously, whether we pursue a treatment or decide to do nothing at all. The answers aren't simple, and the outcomes are life or death. Examining these questions with the compassion of a pediatrician and the rigor of a scientist, Offit reminds us that we all have a role to play in ensuring that medicine upholds its very first principle: to do no harm"--
Subjects: Medical ethics.; Risk assessment.; Pharmacology, Experimental.; Drugs;
Available copies: 1 / Total copies: 1
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Happiness : the crooked little road to semi-ever after : a memoir / by Harpham, Heather Elise,1967-author.;
Subjects: Biographies.; Harpham, Heather Elise, 1967-; Newborn Infants; Blood diseases in pregnancy; Blood; Parent and child;
Available copies: 1 / Total copies: 1
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The Children Act [videorecording] / by Chaplin, Ben,actor.; Eyre, Richard,1954-film director.; Thompson, Emma,actor.; Tucci, Stanley,actor.; Cavaliero, Rosie,actor.; Holmes, Honey,actor.; Amuka-Bird, Nikki,1976-actor.; Watkins, Jason,1966-actor.; Whitehead, Fionn,1997-actor.; Lions Gate Entertainment (Firm),publisher.;
Emma Thompson, Stanley Tucci, Ben Chaplin, Fionn Whitehead, Rosie Cavaliero, Honey Holmes, Nikki Amuka-bird, Jason Watkins.Fiona Maye is a High Court judge in London ruling with wisdom and kindness over ethically complicated cases of family law. Fiona is tasked with ruling on the case of Adam, an exceptional boy who is refusing a life-saving blood transfusion. He is three months from his eighteenth birthday and legally still a child. Fiona visits Adam in the hospital and it has an extreme emotional impact on them both.Canadian Home Video Rating: 14A.MPAA rating: R; for a sexual reference.DVD ; widescreen presentation ; Dolby Digital 5.1.
Subjects: Fiction films.; Feature films.; Great Britain.; Great Britain. High Court of Justice; Women judges; Teenage boys; Jehovah's Witnesses; Blood;
For private home use only.
Available copies: 1 / Total copies: 1
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The serpent in heaven / by Harris, Charlaine,author.;
The granddaughter of Rasputin, Felicia provides the hemophiliac Tsar Alexei with the blood transfusions that keep him alive until she discovers her true heritage and what she is capable of, making her a target in the capital of the Holy Russian Empire where only her courage will keep her alive.
Subjects: Thrillers (Fiction); Alternative histories (Fiction); Novels.; Kidnapping; Magic; Sisters; Witches;
Available copies: 1 / Total copies: 2
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I felt the end before it came : memoirs of a queer ex-Jehovah's Witness / by Cox, Daniel Allen,author.;
Includes bibliographical references.""I spent eighteen years in a group that taught me to hate myself. You cannot be queer and a Jehovah's Witness--it's one or the other." Daniel Allen Cox grew up with firm lines around what his religion considered unacceptable: celebrating birthdays and holidays; voting in elections, pursuing higher education, and other forays into independent thought. Their opposition to blood transfusions would have consequences for his mother, just as their stance on homosexuality would for him. But even years after whispers of his sexual orientation reached his congregation's presiding elder, catalyzing his disassociation, the distinction between "in" and "out" isn't always clear. Still in the midst of a lifelong disentanglement, Cox grapples with the group's cultish tactics--from gaslighting to shunning--and their resulting harms--from simmering anger to substance abuse--all while redefining its concepts through a queer lens. Can Paradise be a bathhouse, a concert hall, or a room full of books? With great candour and disarming self-awareness, Cox takes readers on a journey from his early days as a solicitous door-to-door preacher in Montreal to a stint in New York City, where he's swept up in a scene of photographers and hustlers blurring the line between art and pornography. The culmination of years spent both processing and avoiding a complicated past, I Felt the End Before It Came reckons with memory and language just as it provides a blueprint to surviving a litany of Armageddons."--
Subjects: Biographies.; Autobiographies.; Creative nonfiction.; Cox, Daniel Allen; Cox, Daniel Allen.; Ex-church members; Ex-church members; Gay men; Authors, Canadian (English);
Available copies: 1 / Total copies: 1
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